What Is Type III Collagen?

Type III collagen is a fibrillar collagen found in young, healthy skin. In young skin, Type I to Type III ratio is approximately 3:1. This ratio disrupts with aging as Type III degrades faster than Type I.

Recombinant human Type III collagen (rhCol3) is manufactured through biotechnology, producing identical amino acid sequence to natural human collagen with zero animal-derived risks.

Clinical Benefits (Evidence-Based)

• Improved skin elasticity and firmness
• Reduction in fine lines and wrinkle depth
• Enhanced skin barrier function, reduced TEWL
• Promotes wound healing and post-procedure recovery
• Stimulates natural collagen synthesis by fibroblasts

Type I vs. Type III: Key Differences

• Type I: Tensile strength; 80-90% of body collagen
• Type III: Elasticity and plumpness; degrades faster with age
• Combined: Most effective anti-aging formulations include both types

OEM Product Opportunities

• Post-procedure recovery creams (Class II medical device)
• Premium dual-collagen serums (Type I + III)
• Eye contour creams for crow’s feet
• Lyophilized collagen powder ampoules (>95% purity)
• Sheet masks with high-concentration collagen

Regulatory

• China NMPA: Medical device registration available
• USA FDA: INCI registration; GRAS status
• KFDA: Recognized functional ingredient